About Shanghai Unibio Lab Co., Ltd
1. Company Overview
Shanghai Unibio Lab Probiotics (Helplifes) is a professional probiotic R&D, manufacturing and CDMO enterprise built on 40+ years probiotic research from Jiangnan University, a world-top institution in food microbiology. We own the only national functional food technology platform and cooperate globally with Novozymes, Bayer, Fonterra and other leading biotech brands. Supported by Wuxi Medical College and its affiliated hospitals, we integrate academic research, clinical verification and industrial mass production.
We operate 4 large self-owned manufacturing bases and 1 R&D center in Shanghai, covering total plant area over 300,000 ㎡. Our production equipment includes Asia’s largest fermentation tanks, world-class GEA aseptic disc centrifuges, ultra-large vacuum freeze dryers and exclusive liquid nitrogen cryogenic granulation machines. Annual output reaches 1,800 tons probiotic raw powder & postbiotics, 10 billion capsules and 10 billion tablets/sachets. Our team consists of over 100 professional staff with 20+ years industrialization experience.
2. Massive Proprietary Strain Library
We have built a comprehensive strain bank with over 30,000 microbial strains, including 25,300 primary 16S rRNA strains, 13,720 draft-genome strains and 8,046 full-genome strains. Strains are isolated from longevity elder gut, infant feces, breast milk, traditional fermented food and fresh fruits & vegetables.
We equip more than 30 sets of in vitro, cellular, animal and clinical screening models to evaluate strain functions, covering gut barrier, metabolism, immunity, inflammation, mental health, oral care, heavy metal detoxification and sub-health intervention. Our portfolio contains 189 patented functional strains categorized into gut health, metabolic management, immune regulation, oral health, women’s care, skin care, mental wellness and next-generation probiotics (NGP). Highlight clinical validated strains include Akkermansia muciniphila AH39, Bifidobacterium breve CCFM1025, L. plantarum CCFM1143, L. rhamnosus GG, L. reuteri CCFM1040 and CCFM8724.
3. Core VPro® 5-Layer Microencapsulation Technology
Our self-developed VPro® five-layer embedding technology solves core industrial pain points like acid, bile, oxygen and freezing damage to probiotics:
Micromolecular protective layer: anti-freezing & anti-stress
Prebiotic nutrition layer: support in-vivo proliferation
Liposome enteric adhesion layer: boost intestinal colonization
Acid & enzyme resistant layer: survive gastric digestion
Oxygen & moisture barrier layer: extend shelf stability
This technology lifts freeze-drying survival rate by 40%, prolongs shelf life to 24 months, and achieves fermentation density above 3.5×10¹⁰ CFU/mL with lyophilized powder concentration up to 8.0×10¹¹ CFU/g. Combined with high-density ion-exchange culture, automatic feedback feeding and biofilm stabilization techniques, we deliver ultra-high viable count raw materials suitable for long-distance export and high-temperature food processing.
4. Featured Strains & Clinically Verified Functions
Next-Generation Probiotics Star: Akkermansia muciniphila AH39
US self-affirmed GRAS certified, exclusively for metabolic management. It strengthens intestinal mucus layer, stimulates GLP-1 secretion, improves insulin resistance, lowers blood glucose and fat accumulation, reduces pro-inflammatory IL-6, and balances short-chain fatty acids (acetate & propionate). Widely applied in premium weight management and metabolic health supplements.
Classic Clinical Strains
Bifidobacterium breve CCFM1025: Improves sleep, relieves stress via gut-brain axis, alleviates depression
Lactobacillus reuteri CCFM1040: Reduces allergic rhinitis & asthma symptoms, balances inflammatory cytokines
L. plantarum CCFM8724: Prevents children dental caries, inhibits oral pathogenic bacteria
L. plantarum CCFM1143: Eases diarrhea, regulates intestinal metabolism for body weight control
L. rhamnosus GG: Gold-standard strain for gut immunity, infant digestive care, globally recognized safe
B. longum CCFM760: Relieves constipation, optimizes gut flora, synergizes GLP-1 secretion with AH39
We also provide targeted compound formulas for depression relief, sleep support, allergic immunity, women vaginal health and GLP-1 metabolic management (HelpGut® GLP1 Pre-Pro-Post complex).
5. Full-Range Product Lines
Probiotic raw powder: Single/multi-strain powder, DVS dairy fermentation starters, heat-resistant Bacillus coagulans series
Next-gen probiotic raw materials: A. muciniphila AH39, Clostridium butyricum
Postbiotics & auxiliary materials: Inactivated postbiotic powder, liposomal ProLipo® postbiotics, VPro® encapsulation coating material
Finished private-label products (HelpGut®): Constipation relief capsules, oral care chewable tablets, AH39 metabolic management capsules
Special yeast strain: Saccharomyces boulardii HS5 for diarrhea relief
All products support customized CFU concentration, dosage forms (powder, capsule, tablet, sachet, gummy) and personalized packaging design.
6. Global Compliance & Certifications
We hold complete international qualification documents covering global markets:
ISO 22000, FSSC 22000, GMP food manufacturing certification (SGS)
HALAL & Orthodox Union (OU) Kosher certificates
FDA US food facility registration; Independent sGRAS conclusion for A. muciniphila AH39
All certifications support customs clearance for North America, EU, Southeast Asia, Middle East, Australia and Japan. Every batch undergoes full internal lab testing (viable count, heavy metals, microbial safety) and accepts third-party SGS/Intertek inspection upon client request.
7. Customized CDMO & Global Service
Available Services
OEM, ODM, private label, custom strain blending, formula R&D, packaging design and technical consultation.
MOQ: 1kg for single strain powder; 5kg compound powder; 5,000 bottles for finished HelpGut products
Lead time: 5–7 days for bulk raw materials; 25–35 days for private label finished goods
Trade terms: FOB Shanghai, CIF, DDU, DDP available
After-sales: Free strain technical guidance, batch COA provision, cold chain logistics scheme, 24-hour working hour complaint response
Global Cooperation Cases
We supply bulk strains and finished products to dietary supplement brands, food factories and pharmacy chains across USA, Germany, Thailand, Indonesia, UAE and Saudi Arabia. Our HALAL-certified materials fit Muslim-majority markets, while AH39 GRAS documentation simplifies US customs clearance. Long-term partners achieve stable annual sales growth thanks to consistent strain activity and regulatory-compliant formulations.
8. Core Advantages Summary
Academic-backed strain resources with 30,000+ proprietary strains and complete clinical data
Exclusive VPro® five-layer encapsulation technology for superior strain stability
Large-scale self-owned production bases with full industrialization capacity
Full international certification system covering US, EU, Middle East and Southeast Asia
One-stop CDMO service from strain development, formula design to finished packaging
Professional export team with rich cross-border customs clearance experience
Unibio Lab Probiotics – Your reliable scientific probiotic partner for global health brands.
Our Products
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VPro® 5-Layer Micro-Encapsulated Probiotics Material with Acid & Bile Resistance
Model: VPro®-5L-COAT
Parameters: 1969976241
Inactivated Liposomal Postbiotic Powder for Dietary Supplements
Model: ProLipo-POST
Parameters: 5572072583
Heat-Inactivated Postbiotics Powder 24-Month Shelf Life for Dietary Supplements
Model: UNI-POST-POW
Parameters: 6299920394
GRAS Certified HelpGut Akkermansia AH39 GLP-1 Probiotic Capsules for Middle East Pharmacy Retail
Model: HelpGut-CAP-AH39-GLP1
Parameters: 8185878897
10 Billion CFU Oral Health HelpGut Probiotics Chewable Tablets
Model: HelpGut-TAB-ORAL
Parameters: 5840645397
HelpGut 100B CFU Constipation Relief Probiotic Capsules with Vegetarian HPMC Shell
Model: HelpGut-CAP-CON100B
Parameters: 6288842168
Butyrate-Producing Clostridium Butyricum CCFM1299 Probiotic Powder for Dietary Supplements
Model: CCFM1299
Parameters: 7754242435
Streptococcus Thermophilus ST67 DVS Yogurt Starter For Fermented Dairy
Model: ST67
Parameters: 7327695680
10B-300B CFU/g Streptococcus Thermophilus ST67 DVS Yogurt Starter Powder
Model: ST67
Parameters: 2498781412
ST67 Streptococcus Thermophilus Raw Powder for Dietary Supplement OEM
Model: ST67
Parameters: 1639706569
GRAS Certified Akkermansia Muciniphila AH39 Bulk Probiotic Powder
Model: AH39
Parameters: 8245620637
Bacillus Coagulans CCFM1041 10B CFU/g Heat-Resistant Probiotic Powder
Model: CCFM1041
Parameters: 0887786642
Bacillus Coagulans CCFM1041 100B CFU/g Heat-Resistant Probiotic Powder
Model: CCFM1041
Parameters: 9863238295
Bacillus Coagulans CCFM1041 300B CFU/g Heat-Resistant Probiotic Powder
Model: CCFM1041
Parameters: 7093865135
Ligilactobacillus Salivarius CCFM1215 Probiotic Raw Powder for Gut and Oral Health
Model: CCFM1215
Parameters: 7864634184
Lactobacillus Delbrueckii Subsp. Bulgaricus HB68 Fermentation DVS Powder 10B-200B CFU/g
Model: HB68
Parameters: 6233868645
Lactobacillus Acidophilus L59 Probiotic Powder with VPro 5-Layer Encapsulation 10B-50B CFU/g
Model: L59
Parameters: 2788340230
Lactobacillus Plantarum CCFM1143 Probiotic Bulk Powder for Dietary Supplement
Model: CCFM1143
Parameters: 9696280424
Lactobacillus Plantarum CCFM602 Probiotic Powder 10B-200B CFU/g
Model: CCFM602
Parameters: 0666624534
Lactobacillus plantarum CCFM602 Probiotic Raw Powder for Animal Feed
Model: CCFM602
Parameters: 343531706X
Lactobacillus plantarum CCFM602 Probiotic Powder for Food and Beverage
Model: CCFM602
Parameters: 8202495083
Lactobacillus plantarum CCFM602 Probiotic Raw Powder for Dietary Supplements
Model: CCFM602
Parameters: 9681525779
Oral Health Probiotic Powder with VPro Encapsulation for Chewable Tablets
Model: CCFM8724
Parameters: 7315227113
Lactobacillus plantarum CCFM8724 Powder for Oral Care Supplements
Model: CCFM8724
Parameters: 1102607134
Lactobacillus Plantarum CCFM8661 Probiotic Raw Powder with VPro 5-Layer Encapsulation
Model: CCFM8661
Parameters: 8840775706
Lactobacillus Plantarum CCFM8661 Probiotic Powder for Gut Health and Constipation Relief
Model: CCFM8661
Parameters: 1347582290
Lactobacillus Plantarum HP59 Probiotic Raw Powder 10B-200B CFU/g for Supplement & Fermented Food
Model: HP59
Parameters: 3635490377
Lactobacillus Plantarum HP59 200B CFU/g Probiotic Raw Powder for Gut Health
Model: HP59
Parameters: 7882434159
Lactobacillus Plantarum HP59 10B CFU/g Culture for Yogurt and Fermented Beverage
Model: HP59
Parameters: 8364762273
VPro Encapsulated Lactobacillus Rhamnosus CCFM1219 Probiotic Powder
Model: CCFM1219
Parameters: 1508975620
10B CFU/g Lactobacillus rhamnosus CCFM1219 Probiotic Raw Powder with VPro 5-Layer Encapsulation
Model: CCFM1219
Parameters: 6678303857
100B CFU/g Lactobacillus rhamnosus CCFM1219 Probiotic Raw Powder with VPro 5-Layer Encapsulation
Model: CCFM1219
Parameters: 9841886774
200B CFU/g Lactobacillus rhamnosus CCFM1219 Probiotic Raw Powder with VPro 5-Layer Encapsulation
Model: CCFM1219
Parameters: 9694472490
Bulk Lactobacillus rhamnosus CCFM0528 Probiotic Raw Powder with 10B-200B CFU/g
Model: CCFM0528
Parameters: 0382439899
Human Gut Derived Lactobacillus Rhamnosus CCFM0528 Probiotic Powder with VPro 5-Layer Protection
Model: CCFM0528
Parameters: 3889351956
Infant Care Lactobacillus Rhamnosus GG Probiotic Powder 10B-300B CFU/g
Model: GG
Parameters: 4545514944
B. Adolescentis CCFM1173 Probiotic Raw Powder for Intestinal Health
Model: CCFM1173
Parameters: 9620955676
Bifidobacterium Animalis Subsp. Lactis BL03 Probiotic Powder 10B-600B CFU/g
Model: BL03
Parameters: 9308573976
Bifidobacterium Longum CCFM1195 Probiotic Raw Powder for Food Supplement
Model: CCFM1195
Parameters: 8166874741
Constipation Relief Bifidobacterium Longum CCFM760 Probiotic Raw Powder with VPro Encapsulation
Model: CCFM760
Parameters: 7626035054
Sleep Support Probiotic Powder Bifidobacterium breve CCFM1025 Bulk
Model: CCFM1025
Parameters: 3343277118
HelpGut® Akkermansia Muciniphila AH39 GLP-1 Probiotics
Model: HelpGut-CAP-AH39-GLP1
Parameters: 3585746047
HelpGut® 100B CFU Constipation Relief Probiotic Capsules
Model: HelpGut-CAP-CON100B
Parameters: 0526002670
Company Gallery
Certifications & Awards
Success Stories & Case Studies
Middle East Health Product Wholesaler & Pharmacy Chain Supplier
High customer repurchase rate; GRAS & HALAL certification smooth customs clearance
AH39 with US GRAS approval; customized Arabic packaging & label service provided
Fermented Food & Beverage Manufacturer
Fermentation cycle shortened; product flavor & probiotic activity meet local food standard
Stable fermentation performance; HALAL certified raw materials match local market demand
Overseas Dietary Supplement Brand, Raw Material Distributor
Customer’s product sales increased 42% year-on-year; strain viability stable through shelf life
VPro 5-layer microencapsulation ensures high acid-bile resistance; full third-party test reports supplied
Company & Product Videos
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Customer Testimonials & Success Stories
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